1.
Indian J Physiol Pharmacol
;
2000 Jan; 44(1): 82-6
Article
in English
| IMSEAR
| ID: sea-107451
ABSTRACT
The effect of HD-03 a herbal preparation was studied on galactosamine (400 mg/kg b.wt., i.p.) induced hepatotoxicity in rats. Animals were pre-treated for 14 days with HD-03 and compared against untreated group for SGPT, SGOT, serum bilirubin and liver glycogen. Histopathology of liver lobes was considered to evaluate the extent of hepatic injury induced by galactosamine. These were reversed by HD-03 pre-treatment. HD-03 provided convincing evidence of hepatoprotection against galactosamine induced hapatotoxicity.
Subject(s)
Magnoliopsida/therapeutic use , Animals , Bile Ducts/pathology , Female , Galactosamine , Chemical and Drug Induced Liver Injury/metabolism , Liver/pathology , Liver Function Tests , Male , Necrosis , Phytotherapy , Plant Extracts/therapeutic use , Rats , Rats, Wistar
2.
J Indian Med Assoc
;
1972 Apr; 58(7): 262
Article
in English
| IMSEAR
| ID: sea-102296